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POU2F2‐IL‐31 Autoregulatory Circuit Converts Hepatocytes into the Origin Cells of Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) originates from fully differentiated hepatocytes, but the decisive events for converting hepatocytes to the cells of origin for HCC are still unclear. Liver cancer stem cells (LCSCs) cause HCC but are not bona fide cells of origin. Here, the expressions of POU2F2 and I...

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Detalles Bibliográficos
Autores principales: Yuan, Chunwang, Pang, Lijun, Wang, Wenjing, Ouyang, Yabo, Guo, Xianghua, Liu, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619474/
https://www.ncbi.nlm.nih.gov/pubmed/37733361
http://dx.doi.org/10.1002/advs.202004683