Synthesis and biological evaluation of capsaicin analogues as antioxidant and neuroprotective agents

Capsaicin and its analogues 3a–3q were designed and synthesized as potential new antioxidant and neuroprotective agents. Many analogues exhibited good antioxidant effects, and some showed more potent free radical scavenging activities than the positive drug quercetin (IC(50) = 8.70 ± 1.75 μM for DPP...

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Detalles Bibliográficos
Autores principales: Xie, Mao, Wu, Huixian, Bian, Jing, Huang, Shutong, Xia, Yuanzheng, Qin, Yujun, Yan, Zhiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619477/
https://www.ncbi.nlm.nih.gov/pubmed/37920757
http://dx.doi.org/10.1039/d3ra05107b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619477/
https://www.ncbi.nlm.nih.gov/pubmed/37920757
http://dx.doi.org/10.1039/d3ra05107b

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