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IL-21–producing effector Tfh cells promote B cell alloimmunity in lymph nodes and kidney allografts

Follicular helper T (Tfh) cells have been implicated in controlling rejection after allogeneic kidney transplantation, but the precise subsets, origins, and functions of Tfh cells in this process have not been fully characterized. Here we show that a subset of effector Tfh cells marked by previous I...

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Detalles Bibliográficos
Autores principales: Zhang, Hengcheng, Cavazzoni, Cecilia B., Podestà, Manuel A., Bechu, Elsa D., Ralli, Garyfallia, Chandrakar, Pragya, Lee, Jeong-Mi, Sayin, Ismail, Tullius, Stefan G., Abdi, Reza, Chong, Anita S., Blazar, Bruce R., Sage, Peter T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619486/
https://www.ncbi.nlm.nih.gov/pubmed/37870962
http://dx.doi.org/10.1172/jci.insight.169793