Comparative study in estrogen-depleted mice identifies skeletal and osteocyte transcriptomic responses to abaloparatide and teriparatide

Osteocytes express parathyroid hormone (PTH)/PTH-related protein (PTHrP) receptors and respond to the PTHrP analog abaloparatide (ABL) and to the PTH 1-34 fragment teriparatide (TPTD), which are used to treat osteoporosis. Several studies indicate overlapping but distinct skeletal responses to ABL o...

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Detalles Bibliográficos
Autores principales: Lv, Zhengtao, Zhang, Jiaming, Liang, Shuang, Zhou, Chenhe, Hu, Dorothy, Brooks, Daniel J., Bouxsein, Mary L., Lanske, Beate, Kostenuik, Paul, Gori, Francesca, Baron, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619488/
https://www.ncbi.nlm.nih.gov/pubmed/37870958
http://dx.doi.org/10.1172/jci.insight.161932

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619488/
https://www.ncbi.nlm.nih.gov/pubmed/37870958
http://dx.doi.org/10.1172/jci.insight.161932

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