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Autoreactive B cells in rheumatoid arthritis include mainly activated CXCR3(+) memory B cells and plasmablasts
Many autoimmune diseases (AIDs) are characterized by the persistence of autoreactive B cell responses, which have been directly implicated in disease pathogenesis. How and why these cells are generated or how they are maintained for years is largely unknown. Rheumatoid arthritis (RA) is among the mo...
Autores principales: | Reijm, Sanne, Kwekkeboom, Joanneke C., Blomberg, Nienke J., Suurmond, Jolien, van der Woude, Diane, Toes, René E.M., Scherer, Hans U. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619489/ https://www.ncbi.nlm.nih.gov/pubmed/37725442 http://dx.doi.org/10.1172/jci.insight.172006 |
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