Reverse thiophosphorylase activity of a glycoside phosphorylase in the synthesis of an unnatural Manβ1,4GlcNAc library

β-Mannosides are ubiquitous in nature, with diverse roles in many biological processes. Notably, Manβ1,4GlcNAc a constituent of the core N-glycan in eukaryotes was recently identified as an immune activator, highlighting its potential for use in immunotherapy. Despite their biological significance,...

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Detalles Bibliográficos
Autores principales: Keenan, Tessa, Hatton, Natasha E., Porter, Jack, Vendeville, Jean-Baptiste, Wheatley, David E., Ghirardello, Mattia, Wahart, Alice. J. C., Ahmadipour, Sanaz, Walton, Julia, Galan, M. Carmen, Linclau, Bruno, Miller, Gavin J., Fascione, Martin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619541/
https://www.ncbi.nlm.nih.gov/pubmed/37920340
http://dx.doi.org/10.1039/d3sc04169g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619541/
https://www.ncbi.nlm.nih.gov/pubmed/37920340
http://dx.doi.org/10.1039/d3sc04169g

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