Inhibition of lysosome-tethered Ragulator-Rag-3D complex restricts the replication of Enterovirus 71 and Coxsackie A16

Enterovirus 71 (EV71) and Coxsackie A16 (CVA16) are two major causative agents of hand, foot, and mouth disease (HFMD) in young children. However, the mechanisms regulating the replication and pathogenesis of EV71/CVA16 remain incompletely understood. We performed a genome-wide CRISPR-Cas9 knockout...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Xinhui, Hu, Zhilin, Zhang, Wei, Wu, Shuwei, Hao, Yongjin, Xiao, Xia, Li, Jingjing, Yu, Xiaoliang, Yang, Chengkui, Wang, Jingfeng, Zhang, Huiying, Ma, Feng, Shi, Weifeng, Wang, Jianwei, Lei, Xiaobo, Zhang, Xiaohu, He, Sudan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619577/
https://www.ncbi.nlm.nih.gov/pubmed/37906052
http://dx.doi.org/10.1083/jcb.202303108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619577/
https://www.ncbi.nlm.nih.gov/pubmed/37906052
http://dx.doi.org/10.1083/jcb.202303108

Ejemplares similares