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Successes and challenges in modeling heterogeneous BRAF(V600E) mutated central nervous system neoplasms

Central nervous system (CNS) neoplasms are difficult to treat due to their sensitive location. Over the past two decades, the availability of patient tumor materials facilitated large scale genomic and epigenomic profiling studies, which have resulted in detailed insights into the molecular underpin...

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Detalles Bibliográficos
Autores principales: Xing, Yao Lulu, Panovska, Dena, Petritsch, Claudia K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619673/
https://www.ncbi.nlm.nih.gov/pubmed/37920169
http://dx.doi.org/10.3389/fonc.2023.1223199