GM-CSF-activated STAT5A regulates macrophage functions and inflammation in atherosclerosis

INTRODUCTION: Inhibition of STAT5 was recently reported to reduce murine atherosclerosis. However, the role of STAT5 isoforms, and more in particular STAT5A in macrophages in the context of human atherosclerosis remains unknown. METHODS AND RESULTS: Here, we demonstrate reciprocal expression regulat...

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Detalles Bibliográficos
Autores principales: Nagenborg, Jan, Jin, Han, Ruder, Adele V., Temmerman, Lieve, Mees, Barend, Schalkwijk, Casper, Müller-Klieser, Daniel, Berg, Thorsten, Goossens, Pieter, Donners, Marjo M. P. C., Biessen, Erik A. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619680/
https://www.ncbi.nlm.nih.gov/pubmed/37920458
http://dx.doi.org/10.3389/fimmu.2023.1165306

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619680/
https://www.ncbi.nlm.nih.gov/pubmed/37920458
http://dx.doi.org/10.3389/fimmu.2023.1165306

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