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Validating Trend-Based End Points for Neuroprotection Trials in Glaucoma

PURPOSE: The purpose of this study was to evaluate the power of trend-based visual field (VF) progression end points against long-term development of event-based end points accepted by the US Food and Drug Administration (FDA). METHODS: One eye from 3352 patients with ≥10 24-2 VFs (median = 11 years...

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Detalles Bibliográficos
Autores principales: Montesano, Giovanni, Garway-Heath, David F., Rabiolo, Alessandro, De Moraes, Carlos Gustavo, Ometto, Giovanni, Crabb, David P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619697/
https://www.ncbi.nlm.nih.gov/pubmed/37906055
http://dx.doi.org/10.1167/tvst.12.10.20