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Pangenomic antiviral effect of REP 2139 in CRISPR/Cas9 engineered cell lines expressing hepatitis B virus surface antigen

Chronic hepatitis B remains a global health problem with 296 million people living with chronic HBV infection and being at risk of developing cirrhosis and hepatocellular carcinoma. Non-infectious subviral particles (SVP) are produced in large excess over infectious Dane particles in patients and ar...

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Detalles Bibliográficos
Autores principales: Angelo, Léna, Vaillant, Andrew, Blanchet, Matthieu, Labonté, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619774/
https://www.ncbi.nlm.nih.gov/pubmed/37910550
http://dx.doi.org/10.1371/journal.pone.0293167