Cargando…

Liver sinusoidal endothelial cells show reduced scavenger function and downregulation of Fc gamma receptor IIb, yet maintain a preserved fenestration in the Glmp(gt/gt) mouse model of slowly progressing liver fibrosis

Liver sinusoidal endothelial cells (LSECs) are fenestrated endothelial cells with a unique, high endocytic clearance capacity for blood-borne waste macromolecules and colloids. This LSEC scavenger function has been insufficiently characterized in liver disease. The Glmp(gt/gt) mouse lacks expression...

Descripción completa

Detalles Bibliográficos
Autores principales:	Antwi, Milton Boaheng, Dumitriu, Gianina, Simón-Santamaria, Jaione, Romano, Javier Sánchez, Li, Ruomei, Smedsrød, Bård, Vik, Anders, Eskild, Winnie, Sørensen, Karen Kristine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619817/ https://www.ncbi.nlm.nih.gov/pubmed/37910485 http://dx.doi.org/10.1371/journal.pone.0293526

Ejemplares similares

Age-dependent development of liver fibrosis in Glmp(gt/gt) mice
por: Nesset, Cecilie K., et al.
Publicado: (2016)

Transcriptome and proteome profiling reveal complementary scavenger and immune features of rat liver sinusoidal endothelial cells and liver macrophages
por: Bhandari, Sabin, et al.
Publicado: (2020)

Changes in the proteome and secretome of rat liver sinusoidal endothelial cells during early primary culture and effects of dexamethasone
por: Li, Ruomei, et al.
Publicado: (2022)

The Relationship between Fenestrations, Sieve Plates and Rafts in Liver Sinusoidal Endothelial Cells
por: Svistounov, Dmitri, et al.
Publicado: (2012)

Liver sinusoidal endothelial cells contribute to the uptake and degradation of entero bacterial viruses
por: Øie, Cristina I., et al.
Publicado: (2020)

Autofluorescence in freshly isolated adult human liver sinusoidal cells
por: Larsen, Anett Kristin, et al.
Publicado: (2021)

Efficient Uptake of Blood-Borne BK and JC Polyomavirus-Like Particles in Endothelial Cells of Liver Sinusoids and Renal Vasa Recta
por: Simon-Santamaria, Jaione, et al.
Publicado: (2014)

Lack of the Lysosomal Membrane Protein, GLMP, in Mice Results in Metabolic Dysregulation in Liver
por: Kong, Xiang Yi, et al.
Publicado: (2015)

Search for the Higgs boson in the H ->WW->lvlv channel in ATLAS
por: Armbruster, A
Publicado: (2011)

The Scavenger Function of Liver Sinusoidal Endothelial Cells in Health and Disease
por: Bhandari, Sabin, et al.
Publicado: (2021)

The lysosomal transporter MFSD1 is essential for liver homeostasis and critically depends on its accessory subunit GLMP
por: Massa López, David, et al.
Publicado: (2019)

H->tau tau and H->tau nu with the ATLAS Detector at the LHC
por: Goncalo, R
Publicado: (2011)

Study of H(SUSY) -> Tautau -> l + Tau Jet + Etmis in CMS
por: Kinnunen, Ritva, et al.
Publicado: (1997)

Solar origin of Major GMSs with (-50nT>Dst>-100nT)
por: Kaur, S
Publicado: (2005)

Net widens for funding of <i>arXiv</i>
Publicado: (2010)

Search for the SM Higgs Boson in H->WW->lnu lnu with ATLAS
por: Schmidt, E
Publicado: (2012)

Spitzenforschung im Kleinformat >
Publicado: (2009)

First Observation of the process Z -> tautau -> emu + 4nu with the ATLAS Detector
por: The ATLAS collaboration
Publicado: (2011)

Search for the Higgs boson in the H->WW->lnln decay mode with the ATLAS Detector
por: The ATLAS collaboration
Publicado: (2011)

Data Driven W+jets background estimation for H->WW->llvv(Higgs)
por: Asfandiyarov, R
Publicado: (2012)

<em>Reg</em> reader unlocks secrets of LHC restart
Publicado: (2009)

Study of pp -> jjH with H -> WW -> lepton+neutrino+2 jets in CMS for M(H) = 300 and 600 GeV
por: Yildiz, Hatice, et al.
Publicado: (2001)

Study for a High Level Trigger for the Decay Channel Bs->Ds pi->Phi pi pi->K K pi pi
por: Giassi, Alessandro, et al.
Publicado: (2002)

Manipulating fenestrations in young and old liver sinusoidal endothelial cells
por: Hunt, Nicholas J., et al.
Publicado: (2019)

Liver sinusoidal endothelial cells represents an important blood clearance system in pigs
por: Nedredal, Geir I, et al.
Publicado: (2003)

Search for a Heavy SM Higgs Boson in the H -> ZZ -> llqq Channel at ATLAS
por: Gwilliam, C B
Publicado: (2011)

Measurement of the Z->tau tau and W-> tau nu cross sections with the ATLAS detector
por: Griffiths, J
Publicado: (2011)

Search for H+- gt tau+nu with l+tau(- gt had) and ll final states in CMS
por: Vischia, Pietro
Publicado: (2013)

High Mass Higgs Mtudies Using gg->H and qq->qqH at the LHC
por: Dittmar, Michael, et al.
Publicado: (2001)

Detecting Standard Model Higgs-Boson in the Channel pp -> HW, H -> bb with CMS
por: Drollinger, Volker, et al.
Publicado: (1998)

Study for heavy charged Higgs in pp -> tH+ with H+ -> tau + neutrino in CMS
por: Kinnunen, Ritva
Publicado: (2000)

Search for H->gammagamma at ATLAS
por: Ocariz, José
Publicado: (2011)

Tests of hadronic probes of GT strength
por: García, A, et al.
Publicado: (1992)

Bs->mu+mu- at LHC
por: Sivoklokov, S
Publicado: (2008)

Early failure of the Trifecta GT bioprostheses
por: Tchouta, Lise, et al.
Publicado: (2020)

Search for Stop Pair Production in the Stop -> Chargino B and the Stop -> Neutralino Top Decay Modes
por: Segneri, Gabriele
Publicado: (2003)

Liver sinusoidal endothelial cell ICAM-1 mediated tumor/endothelial crosstalk drives the development of liver metastasis by initiating inflammatory and angiogenic responses
por: Benedicto, Aitor, et al.
Publicado: (2019)

Highly oxidized albumin is cleared by liver sinusoidal endothelial cells via the receptors stabilin-1 and -2
por: Holte, Christopher, et al.
Publicado: (2023)

Searches for the Standard Model Higgs boson in the H->ZZ*->4l decay with the ATLAS detector at the LHC.
por: Prokofiev, K
Publicado: (2008)

Search for a SM Higgs Boson in the Decay H -> WW -> ll with 200 pb-1 at ATLAS
por: Gwilliam, Carl
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_uhtmle0h4qmnid2jhomp4gc86o