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Effect of safranal or candesartan on 3-nitropropionicacid-induced biochemical, behavioral and histological alterations in a rat model of Huntington’s disease

3-nitropropionic acid (3-NP) is a potent mitochondrial inhibitor mycotoxin. Systemic administration of 3-NP can induce Huntington’s disease (HD)-like symptoms in experimental animals. Safranal (Safr) that is found in saffron essential oil has antioxidant, anti-inflammatory and anti-apoptotic actions...

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Detalles Bibliográficos
Autores principales: Shehata, Nagwa Ibrahim, Abd EL-Salam, Dina Mohamed, Hussein, Roqaya Mahmoud, Rizk, Sherine Maher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619823/
https://www.ncbi.nlm.nih.gov/pubmed/37910529
http://dx.doi.org/10.1371/journal.pone.0293660