Screening fructosamine-3-kinase (FN3K) inhibitors, a deglycating enzyme of oncogenic Nrf2: Human FN3K homology modelling, docking and molecular dynamics simulations

Fructosamine-3-kinase (FN3K) is involved in the deglycation of Nrf2, a significant regulator of oxidative stress in cancer cells. However, the intricate functional aspects of FN3K and Nrf2 in breast cancers have not been explored vividly. The objectives of this study are to design the human FN3K pro...

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Detalles Bibliográficos
Autores principales: Beeraka, Narasimha M., Zhang, Jin, Mandal, Subhankar, Vikram P. R., Hemanth, Liu, Junqi, B. M., Namitha, Zhao, Di, Vishwanath, Prashanth, B. M., Gurupadayya, Fan, Ruitai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619859/
https://www.ncbi.nlm.nih.gov/pubmed/37910519
http://dx.doi.org/10.1371/journal.pone.0283705

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619859/
https://www.ncbi.nlm.nih.gov/pubmed/37910519
http://dx.doi.org/10.1371/journal.pone.0283705

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