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LINE-1 retrotransposons drive human neuronal transcriptome complexity and functional diversification

The genetic mechanisms underlying the expansion in size and complexity of the human brain remain poorly understood. Long interspersed nuclear element–1 (L1) retrotransposons are a source of divergent genetic information in hominoid genomes, but their importance in physiological functions and their c...

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Detalles Bibliográficos
Autores principales: Garza, Raquel, Atacho, Diahann A. M., Adami, Anita, Gerdes, Patricia, Vinod, Meghna, Hsieh, PingHsun, Karlsson, Ofelia, Horvath, Vivien, Johansson, Pia A., Pandiloski, Ninoslav, Matas-Fuentes, Jon, Quaegebeur, Annelies, Kouli, Antonina, Sharma, Yogita, Jönsson, Marie E., Monni, Emanuela, Englund, Elisabet, Eichler, Evan E., Gale Hammell, Molly, Barker, Roger A., Kokaia, Zaal, Douse, Christopher H., Jakobsson, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10619931/
https://www.ncbi.nlm.nih.gov/pubmed/37910626
http://dx.doi.org/10.1126/sciadv.adh9543