Phylogenetic modeling of enhancer shifts in African mole-rats reveals regulatory changes associated with tissue-specific traits

Changes in gene regulation are thought to underlie most phenotypic differences between species. For subterranean rodents such as the naked mole-rat, proposed phenotypic adaptations include hypoxia tolerance, metabolic changes, and cancer resistance. However, it is largely unknown what regulatory cha...

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Detalles Bibliográficos
Autores principales: Parey, Elise, Fernandez-Aroca, Diego, Frost, Stephanie, Uribarren, Ainhoa, Park, Thomas J., Zöttl, Markus, St. John Smith, Ewan, Berthelot, Camille, Villar, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620049/
https://www.ncbi.nlm.nih.gov/pubmed/37625847
http://dx.doi.org/10.1101/gr.277715.123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620049/
https://www.ncbi.nlm.nih.gov/pubmed/37625847
http://dx.doi.org/10.1101/gr.277715.123

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