Cargando…
Phylogenetic modeling of enhancer shifts in African mole-rats reveals regulatory changes associated with tissue-specific traits
Changes in gene regulation are thought to underlie most phenotypic differences between species. For subterranean rodents such as the naked mole-rat, proposed phenotypic adaptations include hypoxia tolerance, metabolic changes, and cancer resistance. However, it is largely unknown what regulatory cha...
Autores principales: | Parey, Elise, Fernandez-Aroca, Diego, Frost, Stephanie, Uribarren, Ainhoa, Park, Thomas J., Zöttl, Markus, St. John Smith, Ewan, Berthelot, Camille, Villar, Diego |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620049/ https://www.ncbi.nlm.nih.gov/pubmed/37625847 http://dx.doi.org/10.1101/gr.277715.123 |
Ejemplares similares
-
Independent evolution of pain insensitivity in African mole-rats: origins and mechanisms
por: Smith, Ewan St. John, et al.
Publicado: (2020) -
Absence of histamine-induced itch in the African naked mole-rat and "rescue" by Substance P
por: Smith, Ewan St John, et al.
Publicado: (2010) -
Complexity and conservation of regulatory landscapes underlie evolutionary resilience of mammalian gene expression
por: Berthelot, Camille, et al.
Publicado: (2017) -
Damaraland mole-rats do not rely on helpers for reproduction or survival
por: Thorley, Jack, et al.
Publicado: (2023) -
No task specialization among helpers in Damaraland mole-rats
por: Thorley, Jack, et al.
Publicado: (2018)