Locus-resolution analysis of L1 regulation and retrotransposition potential in mouse embryonic development

Mice harbor ∼2800 intact copies of the retrotransposon Long Interspersed Element 1 (L1). The in vivo retrotransposition capacity of an L1 copy is defined by both its sequence integrity and epigenetic status, including DNA methylation of the monomeric units constituting young mouse L1 promoters. Locu...

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Detalles Bibliográficos
Autores principales: Gerdes, Patricia, Chan, Dorothy, Lundberg, Mischa, Sanchez-Luque, Francisco J., Bodea, Gabriela O., Ewing, Adam D., Faulkner, Geoffrey J., Richardson, Sandra R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620060/
https://www.ncbi.nlm.nih.gov/pubmed/37798118
http://dx.doi.org/10.1101/gr.278003.123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620060/
https://www.ncbi.nlm.nih.gov/pubmed/37798118
http://dx.doi.org/10.1101/gr.278003.123

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