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Structures of a sperm-specific solute carrier gated by voltage and cAMP

The newly characterized sperm-specific Na(+)/H(+) exchanger stands out by its unique tripartite domain composition(1,2). It unites a classical solute carrier unit with regulatory domains usually found in ion channels, namely, a voltage-sensing domain and a cyclic-nucleotide binding domain(1,3), whic...

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Detalles Bibliográficos
Autores principales: Kalienkova, Valeria, Peter, Martin F., Rheinberger, Jan, Paulino, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620091/
https://www.ncbi.nlm.nih.gov/pubmed/37880361
http://dx.doi.org/10.1038/s41586-023-06629-w