Single-nucleus genomics in outbred rats with divergent cocaine addiction-like behaviors reveals changes in amygdala GABAergic inhibition

The amygdala processes positive and negative valence and contributes to addiction, but the cell-type-specific gene regulatory programs involved are unknown. We generated an atlas of single-nucleus gene expression and chromatin accessibility in the amygdala of outbred rats with high and low cocaine a...

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Detalles Bibliográficos
Autores principales: Zhou, Jessica L., de Guglielmo, Giordano, Ho, Aaron J., Kallupi, Marsida, Pokhrel, Narayan, Li, Hai-Ri, Chitre, Apurva S., Munro, Daniel, Mohammadi, Pejman, Carrette, Lieselot L. G., George, Olivier, Palmer, Abraham A., McVicker, Graham, Telese, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620093/
https://www.ncbi.nlm.nih.gov/pubmed/37798411
http://dx.doi.org/10.1038/s41593-023-01452-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620093/
https://www.ncbi.nlm.nih.gov/pubmed/37798411
http://dx.doi.org/10.1038/s41593-023-01452-y

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