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Trapping all ERBB ligands decreases pancreatic lesions in a murine model of pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is among the deadliest of cancers. Attempts to develop targeted therapies still need to be established. Some oncogenic mechanisms in PDAC carcinogenesis harness the EGFR/ERBB receptor family. To explore the effects on pancreatic lesions, we attempted simultane...

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Detalles Bibliográficos
Autores principales: Hedegger, Kathrin, Blutke, Andreas, Hommel, Theresa, Auer, Kerstin E., Nataraj, Nishanth B., Lindzen, Moshit, Yarden, Yosef, Dahlhoff, Maik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620123/
https://www.ncbi.nlm.nih.gov/pubmed/37341059
http://dx.doi.org/10.1002/1878-0261.13473