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Comparative membrane lipidomics of hepatocellular carcinoma cells reveals diacylglycerol and ceramide as key regulators of Wnt/β‐catenin signaling and tumor growth

Hepatocellular carcinoma (HCC) is largely associated with aberrant activation of Wnt/β‐catenin signaling. Nevertheless, how membrane lipid composition is altered in HCC cells with abnormal Wnt signaling remains elusive. Here, by exploiting comprehensive lipidome profiling, we unravel the membrane li...

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Detalles Bibliográficos
Autores principales: Azbazdar, Yagmur, Demirci, Yeliz, Heger, Guillaume, Ipekgil, Dogac, Karabicici, Mustafa, Ozhan, Gunes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620124/
https://www.ncbi.nlm.nih.gov/pubmed/37699867
http://dx.doi.org/10.1002/1878-0261.13520