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Histone‐lysine N‐methyltransferase EHMT2 (G9a) inhibition mitigates tumorigenicity in Myc‐driven liver cancer

Hepatocellular carcinoma (HCC) is the third deadliest and sixth most common cancer in the world. Histone‐lysine N‐methyltransferase EHMT2 (also known as G9a) is a histone methyltransferase frequently overexpressed in many cancer types, including HCC. We showed that Myc‐driven liver tumours have a un...

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Detalles Bibliográficos
Autores principales: Thng, Dexter Kai Hao, Hooi, Lissa, Toh, Clarissa Chin Min, Lim, Jhin Jieh, Rajagopalan, Deepa, Syariff, Imran Qamar Charles, Tan, Zher Min, Rashid, Masturah Bte Mohd Abdul, Zhou, Lei, Kow, Alfred Wei Chieh, Bonney, Glenn Kunnath, Goh, Brian Kim Poh, Kam, Juinn Huar, Jha, Sudhakar, Dan, Yock Young, Chow, Pierce Kah Hoe, Toh, Tan Boon, Chow, Edward Kai‐Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620125/
https://www.ncbi.nlm.nih.gov/pubmed/36896891
http://dx.doi.org/10.1002/1878-0261.13417