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Pellino 3 promotes the colitis‐associated colorectal cancer through suppression of IRF4‐mediated negative regulation of TLR4 signalling

The incidence of colitis‐associated colorectal cancer (CAC) has increased due to a high‐nutrient diet, increased environmental stimuli and inherited gene mutations. To adequately treat CAC, drugs should be developed by identifying novel therapeutic targets. E3 ubiquitin‐protein ligase pellino homolo...

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Detalles Bibliográficos
Autores principales: Kim, Young‐Mi, Kim, Hye‐Youn, Ha Thi, Huyen Trang, Kim, Jooyoung, Lee, Young Jae, Kim, Seong‐Jin, Hong, Suntaek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620127/
https://www.ncbi.nlm.nih.gov/pubmed/37341064
http://dx.doi.org/10.1002/1878-0261.13475