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CRISPR/Cas9 screen for genome‐wide interrogation of essential MYC‐bound E‐boxes in cancer cells

The transcription factor MYC is a proto‐oncogene with a well‐documented essential role in the pathogenesis and maintenance of several types of cancer. MYC binds to specific E‐box sequences in the genome to regulate gene expression in a cell‐type‐ and developmental‐stage‐specific manner. To date, a c...

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Detalles Bibliográficos
Autores principales: Kazimierska, Marta, Podralska, Marta, Żurawek, Magdalena, Woźniak, Tomasz, Kasprzyk, Marta Elżbieta, Sura, Weronika, Łosiewski, Wojciech, Ziółkowska‐Suchanek, Iwona, Kluiver, Joost, van den Berg, Anke, Rozwadowska, Natalia, Dzikiewicz‐Krawczyk, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620128/
https://www.ncbi.nlm.nih.gov/pubmed/37519063
http://dx.doi.org/10.1002/1878-0261.13493