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Chromosomal instability and a deregulated cell cycle are intrinsic features of high‐risk gastrointestinal stromal tumours with a metastatic potential

Patients with localised, high‐risk gastrointestinal stromal tumours (GIST) benefit from adjuvant imatinib treatment. Still, approximately 40% of patients relapse within 3 years after adjuvant therapy and the clinical and histopathological features currently used for risk classification cannot precis...

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Detalles Bibliográficos
Autores principales: Namløs, Heidi Maria, Khelik, Ksenia, Nakken, Sigve, Vodák, Daniel, Hovig, Eivind, Myklebost, Ola, Boye, Kjetil, Meza‐Zepeda, Leonardo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620130/
https://www.ncbi.nlm.nih.gov/pubmed/37622176
http://dx.doi.org/10.1002/1878-0261.13514