ARF1 prevents aberrant type I interferon induction by regulating STING activation and recycling

Type I interferon (IFN) signalling is tightly controlled. Upon recognition of DNA by cyclic GMP-AMP synthase (cGAS), stimulator of interferon genes (STING) translocates along the endoplasmic reticulum (ER)-Golgi axis to induce IFN signalling. Termination is achieved through autophagic degradation or...

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Detalles Bibliográficos
Autores principales: Hirschenberger, Maximilian, Lepelley, Alice, Rupp, Ulrich, Klute, Susanne, Hunszinger, Victoria, Koepke, Lennart, Merold, Veronika, Didry-Barca, Blaise, Wondany, Fanny, Bergner, Tim, Moreau, Tatiana, Rodero, Mathieu P., Rösler, Reinhild, Wiese, Sebastian, Volpi, Stefano, Gattorno, Marco, Papa, Riccardo, Lynch, Sally-Ann, Haug, Marte G., Houge, Gunnar, Wigby, Kristen M., Sprague, Jessica, Lenberg, Jerica, Read, Clarissa, Walther, Paul, Michaelis, Jens, Kirchhoff, Frank, de Oliveira Mann, Carina C., Crow, Yanick J., Sparrer, Konstantin M. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620153/
https://www.ncbi.nlm.nih.gov/pubmed/37914730
http://dx.doi.org/10.1038/s41467-023-42150-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620153/
https://www.ncbi.nlm.nih.gov/pubmed/37914730
http://dx.doi.org/10.1038/s41467-023-42150-4

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