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Preclinical evaluation of [(58m)Co]Co-DOTA-PSMA-617 for Auger electron therapy of prostate cancer

Prostate-specific membrane antigen (PSMA), highly expressed in prostate cancer, is a promising target for radionuclide therapy. Auger electron-emitting radionuclides are well suited for targeted radionuclide therapy if they can be delivered close to the DNA of the targeted cells. This preclinical st...

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Detalles Bibliográficos
Autores principales: Baun, Christina, Dam, Johan Hygum, Hildebrandt, Malene Grubbe, Ewald, Jesper Dupont, Kristensen, Bjarne Winther, Gammelsrød, Vigga Sand, Olsen, Birgitte Brinkmann, Thisgaard, Helge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620164/
https://www.ncbi.nlm.nih.gov/pubmed/37914790
http://dx.doi.org/10.1038/s41598-023-43429-8