Recognition and reprogramming of E3 ubiquitin ligase surfaces by α-helical peptides

Molecules that induce novel interactions between proteins hold great promise for the study of biological systems and the development of therapeutics, but their discovery has been limited by the complexities of rationally designing interactions between three components, and because known binders to e...

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Detalles Bibliográficos
Autores principales: Tokareva, Olena S., Li, Kunhua, Travaline, Tara L., Thomson, Ty M., Swiecicki, Jean-Marie, Moussa, Mahmoud, Ramirez, Jessica D., Litchman, Sean, Verdine, Gregory L., McGee, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620186/
https://www.ncbi.nlm.nih.gov/pubmed/37914719
http://dx.doi.org/10.1038/s41467-023-42395-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620186/
https://www.ncbi.nlm.nih.gov/pubmed/37914719
http://dx.doi.org/10.1038/s41467-023-42395-z

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