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Recognition and reprogramming of E3 ubiquitin ligase surfaces by α-helical peptides
Molecules that induce novel interactions between proteins hold great promise for the study of biological systems and the development of therapeutics, but their discovery has been limited by the complexities of rationally designing interactions between three components, and because known binders to e...
Autores principales: | Tokareva, Olena S., Li, Kunhua, Travaline, Tara L., Thomson, Ty M., Swiecicki, Jean-Marie, Moussa, Mahmoud, Ramirez, Jessica D., Litchman, Sean, Verdine, Gregory L., McGee, John H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620186/ https://www.ncbi.nlm.nih.gov/pubmed/37914719 http://dx.doi.org/10.1038/s41467-023-42395-z |
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