Artificial surface labelling of Escherichia coli with StrepTagII antigen to study how monoclonal antibodies drive complement-mediated killing

Antibodies play a key role in the immune defence against Gram-negative bacteria. After binding to bacterial surface antigens, IgG and IgM can activate the complement system and trigger formation of lytic membrane attack complex (MAC) pores. Molecular studies to compare functional activity of antibod...

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Detalles Bibliográficos
Autores principales: Muts, Remy M., den Boer, Maurits A., Bardoel, Bart W., Aerts, Piet C., de Haas, Carla J. C., Heck, Albert J. R., Rooijakkers, Suzan H. M., Heesterbeek, Dani A. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620216/
https://www.ncbi.nlm.nih.gov/pubmed/37914798
http://dx.doi.org/10.1038/s41598-023-46026-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620216/
https://www.ncbi.nlm.nih.gov/pubmed/37914798
http://dx.doi.org/10.1038/s41598-023-46026-x

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