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An in vitro model of the macrophage-endothelial interface to characterize CAR T-cell induced cytokine storm
Chimeric Antigen Receptor (CAR) T-cell therapy is a highly effective treatment for B-cell malignancies but limited in use due to clinically significant hyperinflammatory toxicities. Understanding the pathophysiologic mechanisms which mediate these toxicities can help identify novel management strate...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620221/ https://www.ncbi.nlm.nih.gov/pubmed/37914765 http://dx.doi.org/10.1038/s41598-023-46114-y |