Cargando…

Essentiality of Nfatc1 short isoform in osteoclast differentiation and its self-regulation

During osteoclast differentiation, the expression of the transcription factor nuclear factor of activated T cell 1 (Nfatc1) increases in an autoproliferative manner. Nfatc1 isoforms are of three sizes, and only the short isoform increases during osteoclast differentiation. Genetic ablation of the wh...

Descripción completa

Detalles Bibliográficos
Autores principales: Omata, Yasuhiro, Tachibana, Hideyuki, Aizaki, Yoshimi, Mimura, Toshihide, Sato, Kojiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620225/
https://www.ncbi.nlm.nih.gov/pubmed/37914750
http://dx.doi.org/10.1038/s41598-023-45909-3