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FTO-mediated LINC01134 stabilization to promote chemoresistance through miR-140-3p/WNT5A/WNT pathway in PDAC

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer most frequently detected at an advanced stage that limits treatment options to systemic chemotherapy, which has provided only marginal positive clinical outcomes. Currently, the first-line chemotherapeutic agent for PDAC is gemcit...

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Detalles Bibliográficos
Autores principales: Lu, Jin, Yang, Yongsheng, Liu, Xiangliang, Chen, Xiao, Song, Wei, Liu, Zefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620239/
https://www.ncbi.nlm.nih.gov/pubmed/37914721
http://dx.doi.org/10.1038/s41419-023-06244-7