Hepatocyte FBXW7-dependent activity of nutrient-sensing nuclear receptors controls systemic energy homeostasis and NASH progression in male mice

Nonalcoholic steatohepatitis (NASH) is epidemiologically associated with obesity and diabetes and can lead to liver cirrhosis and hepatocellular carcinoma if left untreated. The intricate signaling pathways that orchestrate hepatocyte energy metabolism and cellular stress, intrahepatic cell crosstal...

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Detalles Bibliográficos
Autores principales: Xia, Hui, Dufour, Catherine R., Medkour, Younes, Scholtes, Charlotte, Chen, Yonghong, Guluzian, Christina, B’chir, Wafa, Giguère, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620240/
https://www.ncbi.nlm.nih.gov/pubmed/37914694
http://dx.doi.org/10.1038/s41467-023-42785-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620240/
https://www.ncbi.nlm.nih.gov/pubmed/37914694
http://dx.doi.org/10.1038/s41467-023-42785-3

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