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Mesonephric-like adenocarcinoma of the female genital tract: possible role of KRAS-targeted treatment—detailed molecular analysis of a case series and review of the literature for targetable somatic KRAS-mutations

PURPOSE: Mesonephric-like adenocarcinomas (MLA) of the female genital tract represent a rare and relatively recently described neoplasm exhibiting characteristic morphologic and immunohistochemical findings commonly associated with a KRAS-mutation. Most cases display an aggressive clinical behavior,...

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Detalles Bibliográficos
Autores principales: Brambs, Christine E., Horn, Lars-Christian, Hiller, Ruth, Krücken, Irene, Braun, Christian, Christmann, Corina, Monecke, Astrid, Höhn, Anne Kathrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620254/
https://www.ncbi.nlm.nih.gov/pubmed/37668797
http://dx.doi.org/10.1007/s00432-023-05306-9