Efficacy and safety in mice of repeated, lifelong administration of an ANGPTL3 vaccine

Previously, we reported that an ANGPTL3 vaccine is a hopeful therapeutic option against dyslipidemia. In our current study, we assess durability and booster effects of that vaccine over a period representing a mouse’s lifespan. The vaccine remained effective for over one year, and booster vaccinatio...

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Detalles Bibliográficos
Autores principales: Fukami, Hirotaka, Morinaga, Jun, Nakagami, Hironori, Hayashi, Hiroki, Okadome, Yusuke, Matsunaga, Eiji, Kadomatsu, Tsuyoshi, Horiguchi, Haruki, Sato, Michio, Sugizaki, Taichi, Miyata, Keishi, Torigoe, Daisuke, Mukoyama, Masashi, Morishita, Ryuichi, Oike, Yuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620388/
https://www.ncbi.nlm.nih.gov/pubmed/37914738
http://dx.doi.org/10.1038/s41541-023-00770-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620388/
https://www.ncbi.nlm.nih.gov/pubmed/37914738
http://dx.doi.org/10.1038/s41541-023-00770-3

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