Cholesterol mediated ferroptosis suppression reveals essential roles of Coenzyme Q and squalene

Recent findings have shown that fatty acid metabolism is profoundly involved in ferroptosis. However, the role of cholesterol in this process remains incompletely understood. In this work, we show that modulating cholesterol levels changes vulnerability of cells to ferroptosis. Cholesterol alters me...

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Detalles Bibliográficos
Autores principales: Sun, Qi, Liu, Diming, Cui, Weiwei, Cheng, Huimin, Huang, Lixia, Zhang, Ruihao, Gu, Junlian, Liu, Shuo, Zhuang, Xiao, Lu, Yi, Chu, Bo, Li, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620397/
https://www.ncbi.nlm.nih.gov/pubmed/37914914
http://dx.doi.org/10.1038/s42003-023-05477-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620397/
https://www.ncbi.nlm.nih.gov/pubmed/37914914
http://dx.doi.org/10.1038/s42003-023-05477-8

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