Transcriptomic analyses reveal proinflammatory activation of human brain microvascular endothelial cells by aging-associated peptide medin and reversal by nanoliposomes

Medin is a common vascular amyloidogenic peptide recently implicated in Alzheimer’s disease (AD) and vascular dementia and its pathology remains unknown. We aim to identify changes in transcriptomic profiles and pathways in human brain microvascular endothelial cells (HBMVECs) exposed to medin, comp...

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Detalles Bibliográficos
Autores principales: Zhang, Yining, Karamanova, Nina, Morrow, Kaleb T., Madine, Jillian, Truran, Seth, Lozoya, Maria, Weissig, Volkmar, Li, Ming, Nikkhah, Mehdi, Park, Jin G., Migrino, Raymond Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620412/
https://www.ncbi.nlm.nih.gov/pubmed/37914766
http://dx.doi.org/10.1038/s41598-023-45959-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620412/
https://www.ncbi.nlm.nih.gov/pubmed/37914766
http://dx.doi.org/10.1038/s41598-023-45959-7

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