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Comparing P53 expression and genome-wide transcriptome profiling to Comet assay in lymphocytes from melanoma patients and healthy controls

This study compared the expression of TP53 in lymphocytes from malignant melanoma (MM) patients with positive sentinel nodes to healthy controls (HCs) following exposure to various doses of UVA radiation. The Lymphocyte Genome Sensitivity (LGS) assay indicated significant differences in DNA damage i...

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Detalles Bibliográficos
Autores principales: Najafzadeh, Mojgan, Naeem, Parisa, Ghaderi, Nader, Jafarinejad, Shohreh, Karimi, Zahra, Ghaderi, Mehran, Akhbari, Pouria, Ghaderi, Rojan, Farsi, Pedram, Wright, Andrew, Anderson, Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620420/
https://www.ncbi.nlm.nih.gov/pubmed/37914759
http://dx.doi.org/10.1038/s41598-023-44965-z