Cargando…

SLC25A22 as a Key Mitochondrial Transporter Against Ferroptosis by Producing Glutathione and Monounsaturated Fatty Acids

AIMS: Ferroptosis, a type of oxidative cell death driven by unlimited lipid peroxidation, is emerging as a target for cancer therapy. Although mitochondrial dysfunction may lead to ferroptosis, the underlying molecular mechanisms and metabolic pathways for ferroptosis are incompletely understood. He...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Yang, Wang, Yuan, Lin, Zhi, Kang, Rui, Tang, Daolin, Liu, Jiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620438/
https://www.ncbi.nlm.nih.gov/pubmed/37051693
http://dx.doi.org/10.1089/ars.2022.0203