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Intestinal IgA-positive plasma cells are highly sensitive indicators of alloreaction early after allogeneic transplantation and associate with both graft-versus-host disease and relapse-related mortality

Intestinal immunoglobulin A (IgA) is strongly involved in microbiota homeostasis. Since microbiota disruption is a major risk factor of acute graft-versus-host disease (GvHD), we addressed the kinetics of intestinal IgA-positive (IgA(+)) plasma cells by immunohistology in a series of 430 intestinal...

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Detalles Bibliográficos
Autores principales: Scheidler, Lucia, Hippe, Katrin, Ghimire, Sakhila, Weber, Daniela, Weber, Markus, Meedt, Elisabeth, Hoffmann, Petra, Lehn, Petra, Burkhardt, Ralph, Mamilos, Andreas, Edinger, Matthias, Wolff, Daniel, Poeck, Hendrik, Evert, Matthias, Gessner, Andre, Herr, Wolfgang, Holler, Ernst
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620570/
https://www.ncbi.nlm.nih.gov/pubmed/37259539
http://dx.doi.org/10.3324/haematol.2022.282188