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Intestinal IgA-positive plasma cells are highly sensitive indicators of alloreaction early after allogeneic transplantation and associate with both graft-versus-host disease and relapse-related mortality
Intestinal immunoglobulin A (IgA) is strongly involved in microbiota homeostasis. Since microbiota disruption is a major risk factor of acute graft-versus-host disease (GvHD), we addressed the kinetics of intestinal IgA-positive (IgA(+)) plasma cells by immunohistology in a series of 430 intestinal...
Autores principales: | Scheidler, Lucia, Hippe, Katrin, Ghimire, Sakhila, Weber, Daniela, Weber, Markus, Meedt, Elisabeth, Hoffmann, Petra, Lehn, Petra, Burkhardt, Ralph, Mamilos, Andreas, Edinger, Matthias, Wolff, Daniel, Poeck, Hendrik, Evert, Matthias, Gessner, Andre, Herr, Wolfgang, Holler, Ernst |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Fondazione Ferrata Storti
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620570/ https://www.ncbi.nlm.nih.gov/pubmed/37259539 http://dx.doi.org/10.3324/haematol.2022.282188 |
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