Increased retention of functional mitochondria in mature sickle red blood cells is associated with increased sickling tendency, hemolysis and oxidative stress

Abnormal retention of mitochondria in mature red blood cells (RBC) has been recently reported in sickle cell anemia (SCA) but their functionality and their role in the pathophysiology of SCA remain unknown. The presence of mitochondria within RBC was determined by flow cytometry in 61 SCA patients a...

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Detalles Bibliográficos
Autores principales: Esperti, Sofia, Nader, Elie, Stier, Antoine, Boisson, Camille, Carin, Romain, Marano, Muriel, Robert, Mélanie, Martin, Marie, Horand, Françoise, Cibiel, Agnes, Renoux, Céline, Van Bruggen, Robin, Blans, Colin, Dargaud, Yesim, Joly, Philippe, Gauthier, Alexandra, Poutrel, Solène, Romana, Marc, Roussel, Damien, Connes, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2023
Materias:
Article - Red Cell Biology & its Disorders
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620576/
https://www.ncbi.nlm.nih.gov/pubmed/37259576
http://dx.doi.org/10.3324/haematol.2023.282684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620576/
https://www.ncbi.nlm.nih.gov/pubmed/37259576
http://dx.doi.org/10.3324/haematol.2023.282684

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