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Interleukin-27 potentiates CD8(+) T-cell-mediated antitumor immunity in chronic lymphocytic leukemia

Chronic lymphocytic leukemia (CLL) cells are highly dependent on interactions with the immunosuppressive tumor micro-environment (TME) for survival and proliferation. In the search for novel treatments, pro-inflammatory cytokines have emerged as candidates to reactivate the immune system. Among thos...

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Detalles Bibliográficos
Autores principales: Pagano, Giulia, Botana, Iria Fernandez, Wierz, Marina, Roessner, Philipp M., Ioannou, Nikolaos, Zhou, Xiangda, Al-Hity, Gheed, Borne, Coralie, Gargiulo, Ernesto, Gonder, Susanne, Qu, Bin, Stamatopoulos, Basile, Ramsay, Alan G., Seiffert, Martina, Largeot, Anne, Moussay, Etienne, Paggetti, Jerome
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620579/
https://www.ncbi.nlm.nih.gov/pubmed/37345470
http://dx.doi.org/10.3324/haematol.2022.282474