Development of a novel human triculture model of non-alcoholic fatty liver disease and identification of berberine as ameliorating steatosis, oxidative stress and fibrosis

Objectives: Non-alcoholic fatty liver disease (NAFLD) and its progression to non-alcoholic steatohepatitis (NASH) and hepatocarcinoma is a serious and growing problem. However, the development of new therapies is severely hindered by a lack of high-throughput assays for drug testing. Methods: We hav...

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Detalles Bibliográficos
Autores principales: Rafiei, Hossein, Yeung, Michelle, Kowalski, Sara, Krystal, Gerald, Elisia, Ingrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620695/
https://www.ncbi.nlm.nih.gov/pubmed/37927606
http://dx.doi.org/10.3389/fphar.2023.1234300

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620695/
https://www.ncbi.nlm.nih.gov/pubmed/37927606
http://dx.doi.org/10.3389/fphar.2023.1234300

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