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RGMa and Neogenin control dendritic spine morphogenesis via WAVE Regulatory Complex-mediated actin remodeling

Structural plasticity, the ability of dendritic spines to change their volume in response to synaptic stimulation, is an essential determinant of synaptic strength and long-term potentiation (LTP), the proposed cellular substrate for learning and memory. Branched actin polymerization is a major forc...

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Detalles Bibliográficos
Autores principales: Sempert, Kai, Shohayeb, Belal, Lanoue, Vanessa, O’Brien, Elizabeth A., Flores, Cecilia, Cooper, Helen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620725/
https://www.ncbi.nlm.nih.gov/pubmed/37928069
http://dx.doi.org/10.3389/fnmol.2023.1253801