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The EDC4‐XRN1 interaction controls P‐body dynamics to link mRNA decapping with decay

Deadenylation‐dependent mRNA decapping and decay is the major cytoplasmic mRNA turnover pathway in eukaryotes. Many mRNA decapping and decay factors are associated with each other via protein–protein interaction motifs. For example, the decapping enzyme DCP2 and the 5'–3' exonuclease XRN1...

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Detalles Bibliográficos
Autores principales: Brothers, William R, Ali, Farah, Kajjo, Sam, Fabian, Marc R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620763/
https://www.ncbi.nlm.nih.gov/pubmed/37621215
http://dx.doi.org/10.15252/embj.2023113933