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PTEN-induced kinase 1 exerts protective effects in diabetic kidney disease by attenuating mitochondrial dysfunction and necroptosis

Mitochondrial dysfunction plays a pivotal role in diabetic kidney disease initiation and progression. PTEN-induced serine/threonine kinase 1 (PINK1) is a core organizer of mitochondrial quality control; however, its function in diabetic kidney disease remains controversial. Here, we aimed to investi...

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Detalles Bibliográficos
Autores principales: Sung, Min-Ji, An, Hyun-Ju, Ha, Min Heui, Park, Seon Hwa, Jeong, Hye Yun, Baek, Jihyun, Lee, Sang Ho, Lee, Yu Ho, Lee, So-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620829/
https://www.ncbi.nlm.nih.gov/pubmed/37928264
http://dx.doi.org/10.7150/ijbs.83906