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A gonadal gap junction INX-14/Notch GLP-1 signaling axis suppresses gut defense through an intestinal lysosome pathway

Gap junctions mediate intercellular communications across cellular networks in the nervous and immune systems. Yet their roles in intestinal innate immunity are poorly understood. Here, we show that the gap junction/innexin subunit inx-14 acts in the C. elegans gonad to attenuate intestinal defenses...

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Detalles Bibliográficos
Autores principales: Zhang, Xiumei, Wang, Yirong, Cai, Zixin, Wan, Zhiqing, Aihemaiti, Yilixiati, Tu, Haijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10620905/
https://www.ncbi.nlm.nih.gov/pubmed/37928537
http://dx.doi.org/10.3389/fimmu.2023.1249436